Review about the regulation and functions of the DLC family of RhoGAP proteins published in Cellular Signalling News 11/18/24
Dr Daniela Stöhr is speaker at the Cold Spring Harbor Asia Conference on Iron, Reactive Oxygen Species & Ferroptosis in Life, Death & Disease. News 10/14/24
Official kick-off meeting of the „antiviral therapies“ research program funded by the Baden-Württemberg Stiftung News 7/24/24
Jenny Geiger was awarded with a travel price to attend the FASEB conference "Dynamics and Encoding in Cell Signaling". News 6/3/24
Research paper identifying a crosstalk between DNA methylation and adherence junction signaling published in Communications in Biology. News 3/8/24
Joint review on "The present and future of bispecific antibodies for cancer therapy“ published in Nature Reviews Drug Discovery“ News 3/7/24
Invitation e:Med online seminar – Chengzhe Tian, 06 March 2024, 2 pm - Towards a single-cell longitudinal characterization of cancer therapeutic resistance News 3/6/24
Markus Morrison is invited speaker at the FASEB conference on “Dynamics and Encoding in Cell Signaling” in Niagara Falls, USA News 2/1/24
Joint research paper on the effects of TNFR2 activation in a mouse model of multiple sclerosis published in Brain Research Bulletin. News 1/25/24
Dr. Oliver Seifert will give a talk on Bispecific Antibodies at the Cambridge Immuno-Oncology SUMMIT 2024 in April. News 1/22/24
Joint research paper on the evaluation of neutralizing antibodies against SARS-CoV-2 variants of concern, including bispecific antibodies developed at IZI, published in Viruses. News 11/28/23
Dr. Cristiano Guttà is speaker at the "Engineering Intelligence - Cyber Valley at University of Stuttgart" Conference News 11/22/23
Dr. Oliver Seifert is speaker at the PEGS-Europe on eIg-Based Bispecific T Cell-Engagers News 11/13/23
Gavin Fullstone will give a talk at the e:Med Meeting on Systems Medicine, 2023, in Berlin (October 10-11) News 10/5/23
Yun Qiu and Dr Gavin Fullstone were speakers at the Swiss Apoptosis and Autophagy Meeting 2023 News 9/13/23
Joint research paper on TNFR1 antagonist in acute mouse models of neurodegeneration published in Scientific Reports. News 7/31/23
Dr Gavin Fullstone was speaker at the Workshop on Computational Models on Biology and Medicine 2023. News 6/19/23
Joint research paper on quantification of intratumoural heterogeneity via machine-learning models trained on PET-MRI data published in Nature Biomedical Engineering News 6/13/23
Review article published in Frontiers in Cell and Developmental Biology as part of the research topic “In Celebration of Women In Membrane Traffic” News 5/26/23
Nomenclature Committee on Cell Death summarizes links between apoptosis, organismal homeostasis and disease. News 5/9/23
Joint research paper on the effects of sequential treatment with a TNFR2 agonist and a TNFR1 antagonist in a mouse model of multiple sclerosis published in J. Neuroinflamnmation News 5/4/23
Joint research paper co-modulation of TNFR1 and TNFR2 in an animal model of multiple sclerosis published in J. Neuroinflammation. News 5/3/23
Joint research paper on the role of TNFR2 and mTNF in T-cell development published in Nature Immunology News 1/27/23
Review article on “Targeting Co Stimulatory Receptors of the TNF Superfamily for Cancer Immunotherapy“ published in BioDrugs News 1/12/23
Prof Markus Morrison will be speaking at “The Future of Biomedical Research” Lecture Series at the CIPF, Valencia, Spain. News 11/16/22
Prof Markus Morrison joins the Scientific Advisory Board of the research unit “Cancer and Genome: Bioinformatics, Biostatistics and Epidemiology of Complex Systems” at Institut Curie, Paris, France. News 11/16/22
Joint research paper on mammalian display of bispecific TCR-based molecules published in Antibodies News 8/4/22
Paper on half-life extension of antibody fragments with flexible polypeptide tails published in Molecules News 6/7/22
OMTX705, a first-in-class tumor microenvironment-targeted ADC developed by Oncomatryx in collaboration with IZI and other institutions received FDA and AEMPS IND clearance to treat advanced solid tumors News 6/7/22
Baliopharm successfully completed a phase 1 trial of Atrosimab, a TNFR1-selective antagonistic monovalent antibody derivative developed at IZI News 6/7/22
Ellipses licences SRB22 from SunRock Biopharma, an antibody scTRAIL fusion protein developed at IZI News 5/27/22
Research paper on Fc-comprising dual-acting costimulatory duokines published in OncoImmunology News 1/28/22
Joint research paper on focal adhesion kinase and TRAIL resistance published in Cell Death and Disease News 1/20/22
Joint research paper on the role of TNF receptors in CNS pathology published in Journal of Neuroinflammation. News 11/18/21
Joint research paper on half-life extension of anticalins published in Frontiers of Pharmacology News 11/18/21
Research paper on novel trivalent bispecific T-cell engagers published in Journal for Immunotherapy of Cancer. News 11/18/21
Perspectives on bispecific antibodies written bei Brinkmann and Kontermann published in Science News 5/28/21
Roland Kontermann gave a keynote on "bispecific antibodies – fit for purpose“ at the PEGS Boston Conference News 5/13/21
Daniela Stöhr and Cristiano Guttà will contribute to the EMBO Workshop "Dying in self-defense: Cell death signaling in animals and plants" with talks and posters News 4/27/21
Nivetha Krishna Moorthy will give a talk at the 10th UK & Ireland Early Career BBB Virtual Symposium News 11/23/20
Joint research paper on targeted nanobody-scTRAIL fusion protein published in Frontiers in Pharmacology News 6/22/20
Review on selective targeting of TNF receptors as novel therapeutic approach published in Frontiers in Cell and Developmental Biology News 6/22/20
Joint research paper on trafficking of matrix metalloproteinases (MMPs) through the Golgi published in Journal of Cell Biology News 6/2/20
Research paper on a bispecific EGFRxHER3 targeting antibody published in Molecular Cancer Therapeutics News 5/28/20
Joint research paper on selective TNFR1 inhibition in NASH published in Cell Death & Disease News 4/22/20
Joint research paper on a non-canonical function of caspase-8 published in Molecular Cell. News 1/24/20
Roland Kontermann and Jürgen Pleiss from the IBTB receive funding from the University program „Terra incognita“ News 10/25/19
New project funding - MARIE SKŁODOWSKA-CURIE ACTIONS (MSCA) Innovative Training Network (ITN) “SECRET” starts in October News 9/27/19
Oliver Seifert and Alexander Rau will give presentations at the European Antibody Congress 2019 in Basel News 9/23/19
Oliver Seifert will give a talk at at the Bispecific Antibody Pipeline Congress (Washington D.C.) News 7/4/19
Roland Kontermann and Oliver Seifert will give a short course on "the making of bispecific antibodies" at the Bispecific Antibody Pipeline Congress (Washington D.C.) News 7/4/19
Roland Kontermann will give a keynote presentation on bispecific antibodies at the PEGS Boston 2019 News 3/6/19
New Project Funding ‘Epigenetics of Differentiation and EMT’ for Prof. Olayioye and Prof. Jeltsch News 10/17/18
Fabian Richter and Roland Kontermann will give presentations at the European Antibody Congress 2018 in Basel News 9/25/18
Prof. Monilola Olayioye and Prof. Roland Kontermann received funding from the initiative "2+2 Verbundprojekte im Rahmen der Wissenschaftlich-Technologischen Zusammenarbeit" News 9/3/18
Roland Kontermann and Oliver Seifert will give a short course on „The making of bispecific antibodies“ News 7/25/18
Contribution to a study published in Plant Cell by Ismael Sánchez-González and Monilola Olayioye on the fate of m6A RNA degradation products News 6/22/18
Schröder et al. accepted for publication in Proceedings in Applied Mathematics and Mechanics News 4/18/18
Tansi et al. accepted for publication in Biochimica et Biophysica Acta - General Subjects News 3/19/18
Angelika Hausser is invited to become a member of the Editorial Board of Cellular Signalling News 3/12/18
Roland Kontermann is invited speaker at the 2nd Annual Next Gen Immuno-Oncology Congress in London News 2/13/18
Roland Kontermann is invited speaker at the 6th Halle Conference on Recombinant Proteins News 2/13/18
Markus Morrison (Rehm) is invited speaker at the EU- and BMBF-funded 3rd OpenMultiMed Training School (Multi-scale and Multi-level Modelling Methodologies in Biomedicine), Erlangen, Germany, February 2018. News 1/8/18
Dafne Müller is speaker at 2nd Annual Immuneprofiling World Congress, Barcelona, Spain (11-12.October, 2017) News 11/2/17